- European Research Services GmbH - Germany,
- University of Erlangen-Nuremberg - Germany,
- Universitair Medisch Centrum Utrecht - Netherlands,
- Stichting Wageningen Research - Netherlands,
- Bundesanstalt für Materialforschung und -prüfung (BAM) - Germany,
- Agencia Estatal Consejo Superior De Investigaciones Cientificas - Spain,
- National Research Council (Consiglio Nazionale delle Ricerche, CNR) - Italy,
- Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. - Germany,
- Helmholtz-Centre for Environmental Research (UFZ) - Germany,
- Universitaet für Bodenkultur Wien - Austria,
- Instituto Tecnologico Del Embalaje, Transporte Y Logistica - Spain,
- Fundacion Gaiker - Spain,
- Umweltbundesamt (UBA) - Germany,
- Reuther Rudolf - Germany,
- Statens Arbeidsmiljoinstitutt - Norway,
- Det Nationale Forskningscenter For Arbejdsmiljø - Denmark,
- Forschungsverbund Berlin e.V. - Germany,
- Universiteit Leiden - Netherlands,
- Univerza V Ljubljani - Slovenia,
- University of Bayreuth - Germany,
- Universita Degli Studi Di Torino - Italy,
- Università degli Studi di Roma Tor Vergata - Italy,
- Ethnicon Metsovion Polytechnion - Greece,
- Ecamricert SRL - Italy,
- Innosieve Diagnostics BV - Netherlands,
- DECHEMA Gesellschaft für Chemische Technik und Biotechnologie - Germany,
- Université Paris Cité - France
Micro- and nanoplastics (MNPs) can reach aquatic, terrestrial and marine habitats and therefore can be found in food, drinking water, air and environmental media. The effects of MNPs on human health remain understudied. Addressing this, the EU-funded PlasticsFatE project aims to enhance current understanding on the impact of MNPs in the human body. To do this, it will implement a comprehensive measurement and testing programme to improve and validate the performance and applicability of available methods and tools for the identification of MNPs. The project's work will lead to a novel risk assessment strategy and support the health-relevant aims of European strategies for plastics.
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Knowledge Gaps
Bioavailability exposure test methods
Human and environmental effects and toxicity test methods
Environmental risk assessment (ERA)
Monitoring and detection equipment
Characteristics of plastic-general
Biological processes and biotic interactions with plastic
Degradation
Environmental fate and behavior of plastic
Exposure assessment-general
Toxicokinetics, toxicodynamics and metabolism (ADME)
Translocation within organism
Environmental exposure
Effects assessment-general
Human and environmental exposure test methods
Testing considerations-general
Environmental effects and ecotoxicity
Cellular uptake of plastic
Human toxicity
Mode of action (MOA)
Reproductive and teratogenic effects
Genotoxicity test methods
Genotoxicity
Chronic or long-term effects, multiple forms and/or sources
Models to predict toxicity
Bioaccumulation, bioconcentration and persistence
Characterization test methods
Commercial-related uncertainties