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Level International
Plastic types Microplastics Nanoplastics
Funding source European Union SOCIETAL CHALLENGES - Health, demographic change and well-being
Project cost 5.999.252,50 EUR
Period April 2021 - March 2025
Geographical area Europe
Categories Human Exposure Public Health
Tags Microplastic Nanoplastic aquatic marine food water air health
Project partners
  • European Research Services GmbH - Germany,
  • University of Erlangen-Nuremberg - Germany,
  • Universitair Medisch Centrum Utrecht - Netherlands,
  • Stichting Wageningen Research - Netherlands,
  • Bundesanstalt für Materialforschung und -prüfung (BAM) - Germany,
  • Agencia Estatal Consejo Superior De Investigaciones Cientificas - Spain,
  • National Research Council (Consiglio Nazionale delle Ricerche, CNR) - Italy,
  • Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. - Germany,
  • Helmholtz-Centre for Environmental Research (UFZ) - Germany,
  • Universitaet für Bodenkultur Wien - Austria,
  • Instituto Tecnologico Del Embalaje, Transporte Y Logistica - Spain,
  • Fundacion Gaiker - Spain,
  • Umweltbundesamt (UBA) - Germany,
  • Reuther Rudolf - Germany,
  • Statens Arbeidsmiljoinstitutt - Norway,
  • Det Nationale Forskningscenter For Arbejdsmiljø - Denmark,
  • Forschungsverbund Berlin e.V. - Germany,
  • Universiteit Leiden - Netherlands,
  • Univerza V Ljubljani - Slovenia,
  • University of Bayreuth - Germany,
  • Universita Degli Studi Di Torino - Italy,
  • Università degli Studi di Roma Tor Vergata - Italy,
  • Ethnicon Metsovion Polytechnion - Greece,
  • Ecamricert SRL - Italy,
  • Innosieve Diagnostics BV - Netherlands,
  • DECHEMA Gesellschaft für Chemische Technik und Biotechnologie - Germany,
  • Université Paris Cité - France
Description

Micro- and nanoplastics (MNPs) can reach aquatic, terrestrial and marine habitats and therefore can be found in food, drinking water, air and environmental media. The effects of MNPs on human health remain understudied. Addressing this, the EU-funded PlasticsFatE project aims to enhance current understanding on the impact of MNPs in the human body. To do this, it will implement a comprehensive measurement and testing programme to improve and validate the performance and applicability of available methods and tools for the identification of MNPs. The project's work will lead to a novel risk assessment strategy and support the health-relevant aims of European strategies for plastics.

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Knowledge Gaps

Bioavailability exposure test methods

Human and environmental effects and toxicity test methods

Environmental risk assessment (ERA)

Monitoring and detection equipment

Characteristics of plastic-general

Biological processes and biotic interactions with plastic

Degradation

Environmental fate and behavior of plastic

Exposure assessment-general

Toxicokinetics, toxicodynamics and metabolism (ADME)

Translocation within organism

Environmental exposure

Effects assessment-general

Human and environmental exposure test methods

Testing considerations-general

Environmental effects and ecotoxicity

Cellular uptake of plastic

Human toxicity

Mode of action (MOA)

Reproductive and teratogenic effects

Genotoxicity test methods

Genotoxicity

Chronic or long-term effects, multiple forms and/or sources

Models to predict toxicity

Bioaccumulation, bioconcentration and persistence

Characterization test methods

Commercial-related uncertainties

Publications

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